Professor Adejuwon Adewale ADENEYE

Prof. Adejuwon Adewale ADENEYE

MBBS, MSc, PhD, DSc, FIPM, FNYA, FAcadMedS
  • adejuwon.adeneye@lasucom.edu.ng

Academic Background, Trainings, Skills, Positions, Teaching, Achievements (in Summary).

Adejuwon Adewale ADENEYE had his medical undergraduate training at the University of Ilorin (1991-1998) and M.Sc. (Pharmacology) training at Usman Danfodiyo University, Sokoto, for which received Federal Government of Nigeria Postgraduate Scholarship Award. He had his Ph.D. (Pharmacology) training at the University of Lagos (2007-2010) and awarded D.Sc. (Alternative Medicine) by thesis in 2013 with the theses in the fields of Diabetology, Obesity and Toxicology. Prof. Adeneye has over 100 publications in reputable scientific journals (8 of which emanated from his Ph.D. thesis), 2 chapter contributions and 2 published books. Three of his published articles were rated among the SciVerse ScienceDirect Top 25 Hottest Articles between 2006 and 2007. Prof. Adeneye was a Distinguished Visiting Fulbright Research Scholar to the College of Pharmacy, University of Kentucky, U.S.A. (August 2010 – May 2011). He also has to his credit several travel awards and an active member of several local and international learned societies. In 2013, Prof. Adeneye is a recipient of African Union-The World Academy of Science (AU-TWAS) Best Young Researcher Award (Basic Science category) and TWAS Young Affiliate Award (2014-2018 Track Tenure). He once served as the Ag. Head of the Department of Pharmacology (March 1, 2014 – February 28, 2016) as well was Ag. Dean, Faculty of Basic Medical Sciences (March 1, 2016 – February 28, 2018). Prof. Adeneye is a Visiting Research Scholar to the College of Pharmacy, University of Kentucky and University of Arkansas Medical School, Arkansas, both in the U.S. Prof. Adeneye’s significant scientific contributions include landmark discoveries of: (i). a novel alpha-glucosidase inhibitor antihyperglycemic molecule (erinidine) isolated from the seeds of Nigerian medicinal plant, Hunteria umbellata (K. Schum) Hallier (ii). a mechanistic model of implantable closed-loop Blood Glucose Monitoring and Activity-Based Insulin Infusion Pump System (known as “Artificial Pancreas Delivery System”). These discoveries potentially impact therapeutic monitoring and management of diabetes mellitus.

Research Interests/Specialisations

Diabetology, Drug Discovery & Development, Toxicology

Publications

1. A.A. Adeneye, O.E. Olorundare, A.O. Akinyele, S. Soyemi, A. Mgbehoma, I. Okoye, R. Albrecht, J. Ntambi, H. Mukhtar (2021).
Experimental therapeutic evaluation of the African vegetables (Clerodendrum volubile leaf and Irvingia gabonensis seed extracts) in trastuzumab-mediated hepato-renal dysfunction in Wistar rats. Asian Journal of Pharmaceutical & Clinical Research 14(1): 147-157;
doi:10.22159/ajpcr.2021.v14i1.40118.

Experimental therapeutic evaluation of the African vegetables (Clerodendrum volubile leaf and Irvingia gabonensis seed extracts) in trastuzumab-mediated hepato-renal dysfunction in Wistar rats. Asian Journal of Pharmaceutical & Clinical Research 14(1): 147-157;

doi:10.22159/ajpcr.2021.v14i1.40118.

2. E.O. Olorundare, A.A. Adeneye, A.O. Akinsola, A.M. Ajayi, O.A. Agede, S.S. Soyemi, A.I. Mgbehoma, I.I. Okoye, R.M. Albrecht, J.M. Ntambi, P.A. Crooks (2021).
Therapeutic potentials of selected antihypertensive agents and their fixed-dose combinations against trastuzumab-mediated cardiotoxicity. Frontiers in Pharmacology 11, Article ID 610331;
https://doi.org/10.3389/fphar.2020.610331

Therapeutic potentials of selected antihypertensive agents and their fixed-dose combinations against trastuzumab-mediated cardiotoxicity. Frontiers in Pharmacology 11, Article ID 610331; https://doi.org/10.3389/fphar.2020.610331

3. O.E. Olorundare, A.A. Adeneye, A.O. Akinsola, D.A. Sanni, M. Koketsu, H. Mukhtar (2020).
Clerodendrum volubile ethanol leaf extract: A potential antidote to doxorubicin-induced cardiotoxicity in rats. Journal of Toxicology volume 2020, Article ID 8859716, 17 pages;
https://doi.org/10.1155/2020/8859716

Clerodendrum volubile ethanol leaf extract: A potential antidote to doxorubicin-induced cardiotoxicity in rats. Journal of Toxicology volume 2020, Article ID 8859716, 17 pages; https://doi.org/10.1155/2020/8859716

4. A.A. Adeneye, J.A. Olagunju, B.A. Murtala (2019).
Evaluation of male fertility-enhancing activities of water seed extract of Hunteria umbellata in Wistar rats. Evidence-Based Complementary and Alternative Medicine vol. 2109, Article ID 7693010, 10 pages;
https://doi.org/10.1155/2019/7693010

Evaluation of male fertility-enhancing activities of water seed extract of Hunteria umbellata in Wistar rats. Evidence-Based Complementary and Alternative Medicine vol. 2109, Article ID 7693010, 10 pages; https://doi.org/10.1155/2019/7693010

5. A.A. Adeneye, J.A. Olagunju, O. Babatunde, O. Oluyemi, O. Awosope, G. Oyekunle, H. Ayuba, O. Omoregie, O. Omole (2019).
Morinda lucida stem bark aqueous extract ameliorates hepato-renal dysfunction in experimental diabetes model. Nigerian Journal of Physiological Sciences 34(1), 33-42;
PMID: 31449269

 Morinda lucida stem bark aqueous extract ameliorates hepato-renal dysfunction in experimental diabetes model. Nigerian Journal of Physiological Sciences 34(1), 33-42; PMID: 31449269

6. A.A. Adeneye, A.S. Benebo (2016).
 Chemopreventive effect of Tadalafil against cisplatin-induced nephrotoxicity in rats. Nigerian Journal of Physiological Sciences 31: 1-10;
PMID: 27574758

Chemopreventive effect of Tadalafil against cisplatin-induced nephrotoxicity in rats. Nigerian Journal of Physiological Sciences 31: 1-10; PMID: 27574758

7. O. Awodele, A.A. Adeneye, S.A. Aiyeola, A.S. Benebo (2015).
Modulatory effect of Mangifera indica against carbon tetrachloride-induced kidney damage in rats. Interdisciplinary Toxicology 8(4): 175-183;
doi: 10.1515/intox-2015-0027.

Modulatory effect of Mangifera indica against carbon tetrachloride-induced kidney damage in rats. Interdisciplinary Toxicology 8(4): 175-183;

doi: 10.1515/intox-2015-0027

8. A.A. Adeneye, P.A. Crooks, Z. Fadhel-Albayati, A.F. Miller, S.W. Zito, O.O. Adeyemi, E.O. Agbaje (2013)
Antihyperglycemic profile of erinidine isolated from Hunteria umbellata seed. African Journal of Traditional, Complementary and Alternative Medicine 10(2): 189-202;
PMID: 24146442; PMCID: PMC3746566

Antihyperglycemic profile of erinidine isolated from Hunteria umbellata seed. African Journal of Traditional, Complementary and Alternative Medicine 10(2): 189-202; PMID: 24146442; PMCID: PMC3746566

9. A.A. Adeneye, O.O. Adeyemi, E.O. Agbaje, M.O. Sofidiya (2012).
The novel antihyperglycemic action of Hunteria umbellata seed fractions mediated via intestinal glucose uptake inhibition. African Journal of Traditional, Complementary and Alternative Medicine 9(1): 17-24;
doi: 10.4314/ajtcam.v9i1.3

The novel antihyperglycemic action of Hunteria umbellata seed fractions mediated via intestinal glucose uptake inhibition. African Journal of Traditional, Complementary and Alternative Medicine 9(1): 17-24; doi: 10.4314/ajtcam.v9i1.3

10. A.A. Adeneye, O.P. Ajagbonna, T.I. Adeleke, S.O., Bello (2006)..
Preliminary toxicity and phytochemical studies of the stem bark aqueous extract of Musanga cecropioides in rats. Journal of Ethnopharmacology 105(3): 374–379;
doi: 10.1016/j.jep.2005.11.027

Preliminary toxicity and phytochemical studies of the stem bark aqueous extract of Musanga cecropioides in rats. Journal of Ethnopharmacology 105(3): 374–379;

doi: 10.1016/j.jep.2005.11.027